The clinical laboratory has from the beginning been a major focus for the application of ICT to its support of healthcare activities but that focus has generally considered the clinical lab as a bounded domain and has only recently began considering  the clinical lab as an integrated subdomain of the EHR. Beginning in 1984 the American Association for Clinical Chemistry (AACC) established a Laboratory Information Systems and Medical Informatics Division which has strived to develop an active program with industrial members. In 1999 the AACC Point-of-Care-Testing (POCT) Division developed a joint industrial standards program with industrial members interested in the connectivity of POCT devices with Clinical Lab Information Management Systems (CLIMS) or Lab Information Systems (LIS). This AACC Division has continued  joint work with this standards activity after its transfer to NCCLS, an ANSI HISB SDO member. Another complementary effort has been that in terminology of the College of American Pathologists and the work that began as the Systematic Nomenclature of Pathology (SNOP) and has evolved into the Systematized Nomenclature of Medicine (SNOMED) that now is included in the National Library of Medicine  (NLM) Unified Medical Language System (UMLS). The American Society of Clinical Laboratory Scientists (ASCLS) also works closely with the AACC on programs for Health Informatics and the EHR.